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Systemic ALCL is a rare disease. There are estimated to be between 2,000 and 5,000 new cases per year in the United States. ALCL accounts for 2% to 8% of adult cases of non-Hodgkin lymphoma, but about 30% of non-Hodgkin lymphoma in children. The disease begins most commonly either in teenagers and young adults in their twenties or in individuals in their sixties or older, but may occur at any age. What are the symptoms of systemic ALCL?The most common early symptom of systemic ALCL is painless swelling of the lymph nodes, usually in the neck, armpit, groin or in the abdomen. Occasionally, the disease may start in a site other than the lymph nodes. The disease may spread to other organs including the bone marrow (30%), skin (20%), lung or liver (10%) or, rarely, other sites such as the gut. Symptoms commonly include fever, night sweats, excessive tiredness, indigestion and abdominal pain, loss of appetite and bone pain. |
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